Unusual Papillary Lymphoid Hyperplasia of The Palatine Tonsil Associated with Ebstein Barr Virus Infection in a Child: A Case Report

We describe the case of an Italian, Caucasian nine-year-old girl, suffering from a unilateral tonsillar swelling. Histopathological and immune-histochemical exams show a lymphoepithelial reactive hyperplasia overlap with a chronicle inflammation.

Microbiologic swaps reveal a throat infection caused by Streptococcus pyogenes, and a probable viral infection, caused by Ebstein Barr Virus (EBV). We underline the importance to recognise and consider this benign lesion due to its similarities with a malignant neoplastic form, especially during differential diagnosis of cervical swellings in young women. This is one of the rare cases described in scientific literature in the last years, especially among caucasian race.


Andrea Borromini*, Alessandro Marchesi, Gloria Golinelli, Maurizio Salvadore, Mascia Verzeletti, Francesca Andrea Bonarrigo, Nicolas Martinelli, Michela Todeschini and Gianpaolo Mirri

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